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Prof. Dr. Basri Çakıroğlu

Enlarged Prostate (BPH): Symptoms, Tests and Which Treatment Fits
Prostate Health8 min readOctober 1, 2026

Enlarged Prostate (BPH): Symptoms, Tests and Which Treatment Fits

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Prof. Dr. Basri ÇakıroğluOnaylı Uzman

Üroloji & Robotik Cerrahi Uzmanı | Hisar Hospital Intercontinental

Waking at night, a weak stream, difficulty starting — benign prostatic hyperplasia affects most men over 50. What the tests mean, when medication is enough, and how to choose between HoLEP, Rezum and surgery.

What Benign Prostatic Hyperplasia Means

The prostate sits directly below the bladder and surrounds the urethra. From around the age of 40 it slowly enlarges under hormonal influence. This growth is not cancer; it is benign prostatic hyperplasia (BPH). The problem is mechanical: the enlarged tissue squeezes the channel urine passes through, and over the years the bladder has to work harder to push against it.

BPH affects roughly half of men over 50 and the large majority over 70. Not every enlarged prostate needs treatment. What matters is not the size of the gland but how much it disturbs your life and whether it is damaging the bladder or kidneys.

The Symptoms

They usually begin quietly and worsen over years, which is why many men dismiss them as "getting older". They fall into two groups:

Obstructive (emptying) symptoms

  • Hesitancy — waiting for the stream to start
  • A weak, thin or interrupted stream
  • Dribbling at the end
  • The feeling that the bladder is not empty
  • Needing to strain
  • Irritative (storage) symptoms

  • Frequency — passing urine more than eight times a day
  • Nocturia — waking at night to urinate, the symptom that most often ruins sleep
  • Sudden, hard-to-postpone urgency
  • Not reaching the toilet in time
  • Severity is measured with the IPSS (International Prostate Symptom Score), a seven-question form: under 8 is mild, 8-19 moderate, 20 and above severe. Filling it in before your appointment makes the conversation far more precise.

    What Happens If It Is Left

    Untreated obstruction does more than reduce quality of life. The bladder muscle thickens, then gradually weakens. In advanced cases:

  • Acute urinary retention — suddenly being unable to pass urine at all, requiring an emergency catheter
  • Recurrent urinary infections and bladder stones
  • Visible blood in the urine
  • Urine retained permanently in the bladder, back-pressure on the kidneys (hydronephrosis) and loss of kidney function
  • Once any of these appears, treatment is no longer a matter of preference.

    The Tests That Matter

    1. History and the IPSS questionnaire

    2. Digital rectal examination — size, consistency, any suspicious firmness

    3. PSA blood test, to rule out prostate cancer

    4. Urine analysis

    5. Uroflowmetry — a peak flow below 10 ml per second suggests obstruction

    6. Ultrasound for prostate volume and post-void residual urine

    Together these confirm BPH and separate it from conditions that cause similar symptoms: bladder cancer, urethral stricture, overactive bladder or a neurological cause.

    When Medication Is Enough

    For moderate symptoms without complications, drugs are the first step.

  • Alpha blockers (tamsulosin, silodosin, alfuzosin) relax the muscle in the prostate and bladder neck and improve flow within days. They do not shrink the prostate. Dizziness and absent ejaculation are possible side effects.
  • 5-alpha reductase inhibitors (finasteride, dutasteride) shrink the gland by about a quarter over 6-12 months and suit prostates above 40 ml. They act slowly and may reduce libido and erectile quality. They also halve PSA, so follow-up values must be doubled when interpreted.
  • The two groups are often combined. Where nocturia dominates, limiting evening fluids, caffeine and alcohol helps. Men who also have erectile difficulty may benefit from tadalafil, which addresses both.

    When Surgery Becomes the Answer

    Surgery is considered when symptoms persist despite medication or side effects are intolerable, and whenever retention, recurrent infection, stones, bleeding or kidney back-pressure has appeared.

    Almost all operations today are endoscopic, through the urethra, with no external incision:

    HoLEP (holmium laser enucleation). The enlarged tissue is separated from its capsule in one piece and removed. Works at any prostate size, including 150-200 ml glands that would once have required open surgery. Low bleeding risk makes it one of the safest choices for men on blood thinners, and re-growth is very unlikely because the whole adenoma is taken out. Catheter usually comes out within 24-48 hours. The common trade-off is retrograde ejaculation.

    Rezum (water vapour therapy). A few seconds of steam injected into the prostate shrink the tissue. Day-case, under local anaesthesia, with a high chance of preserving ejaculation. Suited to small and medium glands; the effect appears over weeks.

    TUR-P. The long-established endoscopic method, cutting tissue piece by piece with electrical energy. Generally limited to prostates under 80 ml, with higher bleeding and re-growth rates than laser enucleation.

    Robotic or laparoscopic simple prostatectomy. For very large glands where endoscopic enucleation is not suitable.

    The right choice depends on prostate size, your age, medications, other conditions and how much weight you place on preserving ejaculation. This is a decision made together, not a ranking.

    Planning Treatment from Abroad

    Your uroflowmetry, ultrasound (prostate volume and residual urine) and PSA can be reviewed before you travel, so the recommended method and the length of stay are known in advance. HoLEP typically requires 4-5 days in Istanbul; the dedicated guide on that operation covers the stay and recovery day by day.

    This article is for general information only and does not replace a medical consultation. Treatment decisions are made after an individual evaluation of your reports and examination.

    Topic Tags:
    enlarged prostate treatmentBPH symptomsbenign prostatic hyperplasianocturia treatmentweak urine streamprostate medication vs surgeryBPH treatment TurkeyIPSS score

    Related Treatment

    Prostate Diseases & Laser Therapies

    Frequently Asked Questions

    Does an enlarged prostate turn into cancer?
    No. Benign prostatic hyperplasia and prostate cancer are different diseases, and BPH does not become cancer. They can coexist, which is why men with prostate symptoms are also assessed with a PSA test and examination.
    Do I have to take prostate medication for life?
    Medication controls symptoms rather than removing the prostate, so it is usually continued for as long as it works. Symptoms generally return if it is stopped. Men who want a definitive solution, or who do not benefit from drugs, are offered surgery.
    Which operation is best for a large prostate?
    HoLEP is size-independent and is routinely performed on glands of 150-200 ml, avoiding open surgery. TURP is generally limited to prostates under 80 ml, and Rezum suits small to medium glands.
    Will treatment affect my sex life?
    Erectile function is generally preserved after laser enucleation, but most men experience retrograde ejaculation — semen passes into the bladder. This is harmless and does not remove the sensation of orgasm, though it matters for men planning children. Rezum has a higher chance of preserving normal ejaculation.
    When should I see a urologist?
    As soon as nocturia, a weak stream or frequency begins to affect daily life, regardless of age. Even without symptoms, an annual prostate check is advised from 50 — or from 45 with a family history of prostate cancer.

    Sources & Guidelines

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